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Microbiome

A Healthy Gut is…
Immune Health Digestive Health Phytonutrients

A Healthy Gut is…

For those involved in functional medicine, the significance of the human gut in the onset, persistence, and exacerbation of various health disorders is well established. A comprehensive care package often includes strategies for healing a dysfunctional gut, focusing on restoring the community of microorganisms and their connections both locally and systemically. While there are numerous safe and effective interventions available, the definition of a "healthy gut" can vary significantly among practitioners...
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Cardiovascular Disease and Gut Microbiota
Probiotics Cardiovascular Health

Cardiovascular Disease and Gut Microbiota

The dark matter of the gastrointestinal microbiome, where yet to be fully discovered bacteria reside, is being steadily explored and some of the related inhabitants have been linked to the production of an enzyme that can convert artery clogging cholesterol into a more harmless form that is not absorbed by the body. In two groundbreaking studies published in Nature Microbiology and Cell, researchers have uncovered the potential of specific gut bacteria to reduce cholesterol levels, paving the way...
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Lifestyle factors for the prevention and care of people with inflammatory bowel disease
Digestive Health Lifestyle Medicine Diets

Lifestyle factors for the prevention and care of people with inflammatory bowel disease

Crohn’s disease (CD) and ulcerative colitis (UC) are chronic inflammatory bowel diseases (IBD) typically featuring chronic diarrhoea (with or without bleeding), abdominal pain, and weight loss. These affect an estimated 3.1 million adults in the USA and another 1.3 million in Europe[1],[2]. Globally, the incidence of IBD is increasing, particularly in newly industrialised countries[3]. These diseases are characterised by chronic inflammation of the gastrointestinal tract. However, other symptoms...
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Leveraging diet to engineer the gut microbiome to manage inflammation
Immune Health Digestive Health Probiotics

Leveraging diet to engineer the gut microbiome to manage inflammation

The gut microbiome, i.e., the community of bacteria and other microorganisms living in the human gut, has been implicated both directly and indirectly (mediating the effects of diet) on human health.  Differences in gut microbiome composition and function have been associated with a variety of chronic diseases ranging from gastrointestinal inflammatory and metabolic conditions to neurological, autoimmunity, cardiovascular, and respiratory illnesses[1]. Headline Takeaways Gut microbiome composition...
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Blood Sugar and Metabolism
Immune Health Metabolism Digestive Health

Blood Sugar and Metabolism

Recent articles in various journals have highlighted the challenge mere mortals have matching their metabolic needs with the foods they trust and like. When to eat In September 2022, a study from the University of Aberdeen, published in the journal Cell Metabolism, caused a stir by potentially dispelling a food timing myth[1]. It looked at the time of day people ate and whether it had any impact on metabolism and weight management. You see, Back in 2013 another study found that calories ingested...
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The ‘cross talk’ between sleep, nutrition, and immunity
Immune Health Food Diets Sleep

The ‘cross talk’ between sleep, nutrition, and immunity

Sleep affects various immune parameters, and is associated with reduced infection risk and can improve infection outcome, autoimmunity, and vaccination responses[1]. Adequate nutrition is an essential factor that also supports the immune system[2]. Not only as it provides fuel for rapidly metabolising immune cells, but also many micronutrients operate as regulators of the immune system, including the generation of cytokines, antibodies, and many immune-active proteins and metabolites. Many modifiable...
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Artificial Sweeteners Attack Health Via the Microbiome
Weight management Diets

Artificial Sweeteners Attack Health Via the Microbiome

Oh Boy… the journal Nature has this week (9.10.14) identified the insidious effect of consuming ‘diet’ or non caloric sweeteners on the burgeoning mass of human adipocytes and they have really taken a good run at it.[1] Non-caloric artificial sweeteners (NAS) were introduced over a century ago as means for providing sweet taste to foods without the associated high energy content of caloric sugars. NAS consumption gained much popularity owing to their reduced costs, low caloric intake and perceived...
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