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Inflammation

Exploring the Connection Between Visceral Fat and Alzheimer’s Disease: A Comprehensive Review
Brain Health Antioxidants Nervous System

Exploring the Connection Between Visceral Fat and Alzheimer’s Disease: A Comprehensive Review

Alzheimer’s disease (AD) is a growing global health issue, exacerbated by aging populations and a lack of definitive treatments.[1] Recent studies, including those by Dolatshahi et al. (2024), have highlighted a potential link between visceral fat and AD. This emerging association suggests that addressing modifiable metabolic risk factors could play a critical role in mitigating Alzheimer’s risk. Accumulation of visceral fat in midlife, particularly in the 40s and 50s, may indicate underlying brain...
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The Gut-Brain Connection: Advancing Health Through Nutrition
Immune Health Digestive Health Nervous System

The Gut-Brain Connection: Advancing Health Through Nutrition

Recent scientific discoveries have unveiled a profound link between gut health and brain function, positioning dietary choices and gastrointestinal well-being at the forefront of overall health.[1] This connection is particularly significant in two areas: the use of probiotics for digestive health[2] and the application of neuronutrition in stroke recovery[3]. Probiotics and the Aryl Hydrocarbon Receptor A groundbreaking study published in Foods has shed light on how probiotics influence gut health...
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Inhibit Il-11 and live longer?
Ageing

Inhibit Il-11 and live longer?

A study in Nature in July 2024[1], raised the idea that blocking the interleukin 11 (IL-11) by using an IL-11 antibody could be a proposition for a healthy increase in lifespan, based on the outcomes in their experimental mouse subjects. As you would expect, IL-11 has a role in the induction and promotion of inflammation an underlying defensive mechanism that is amplified as we age and release more damaged proteins and other molecules in what is known as sterile inflammation. This soup of cellular...
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Immunometabolism – Nutrition is Key
Immune Health Metabolism

Immunometabolism – Nutrition is Key

Disrupted immunometabolism: The hidden culprit behind complex health issues Nutrition plays a critical role in maintaining a healthy and properly functioning immune system. The complex relationship between diet, nutrients, and immunity has significant implications for preventing and managing various diseases, from infections to chronic conditions like diabetes and cancer. Impact of micronutrients on immune function Micronutrients such as vitamins A, C, D, E, B6, B12, folate, and minerals like zinc...
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Turmeric and its Polyphenol Curcumin is Calling You
Ageing Digestive Health

Turmeric and its Polyphenol Curcumin is Calling You

This natural polyphenol is universally known as the “wonder drug of life” [1] and has a long history of medicinal applications; 5,000 (Ayurveda) and 2,000 (Atharveda) years, respectively[2]. Throughout ancient times in the Far East, turmeric was used to treat inflammatory conditions of various organs, for liver and digestive tract problems, and for wound healing. In the 1970s, the first research on the yellow polyphenolic pigment from the Curcuma longa L. (turmeric) rhizome known as curcumin and...
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Magnesium and its Crucial Role in Human Well-Being: Unveiling Subclinical Deficiency in the UK
Metabolism Energy Stress Management

Magnesium and its Crucial Role in Human Well-Being: Unveiling Subclinical Deficiency in the UK

Magnesium (Mg) is a well-understood, essential mineral that plays a pivotal role in various physiological processes within the human body. While it often takes a backseat to well-known minerals like calcium and potassium, Magnesium is equally vital for maintaining overall health. Magnesium is Crucial Magnesium is also essential in plants where it is associated with chlorophyll pigments and serves as a cofactor of enzymes implicated in photosynthesis and metabolism. It is an equally essential nutrient...
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Lifestyle factors for the prevention and care of people with inflammatory bowel disease
Digestive Health Lifestyle Medicine Diets

Lifestyle factors for the prevention and care of people with inflammatory bowel disease

Crohn’s disease (CD) and ulcerative colitis (UC) are chronic inflammatory bowel diseases (IBD) typically featuring chronic diarrhoea (with or without bleeding), abdominal pain, and weight loss. These affect an estimated 3.1 million adults in the USA and another 1.3 million in Europe[1],[2]. Globally, the incidence of IBD is increasing, particularly in newly industrialised countries[3]. These diseases are characterised by chronic inflammation of the gastrointestinal tract. However, other symptoms...
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Gastro Updates
Metabolism Digestive Health Food Lifestyle Medicine

Gastro Updates

It’s the very nature of the type of clinical care that practitioners who use nutrition as a key mechanism of clinical care that the gastrointestinal tract becomes central to interventional strategy. Whilst the gut is not always front and centre there is an inevitable engagement and understanding that all that is, or may be happening, in these remarkable tissues is an ongoing quest. One area that those involved in the care of people with inflammatory bowel conditions have long recognised is that psychological...
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The ‘cross talk’ between sleep, nutrition, and immunity
Immune Health Food Diets Sleep

The ‘cross talk’ between sleep, nutrition, and immunity

Sleep affects various immune parameters, and is associated with reduced infection risk and can improve infection outcome, autoimmunity, and vaccination responses[1]. Adequate nutrition is an essential factor that also supports the immune system[2]. Not only as it provides fuel for rapidly metabolising immune cells, but also many micronutrients operate as regulators of the immune system, including the generation of cytokines, antibodies, and many immune-active proteins and metabolites. Many modifiable...
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SCFAs and Skin Health
Digestive Health Probiotics Diets

SCFAs and Skin Health

‘It’s easier to fool people than to convince them they have been fooled’ attributed to Mark Twain The relationship between the gut and skin health has been one of contention for several years. Primarily the mechanism requires there to be an agreement that the outcome of digestion impacts skin quality. This may seem an obvious connection, but for many people, this is either not understood or denied, often supported by well-meaning clinicians who are also unaware of the important connection A paper...
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