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Obesity

Exploring the Connection Between Visceral Fat and Alzheimer’s Disease: A Comprehensive Review
Brain Health Antioxidants Nervous System

Exploring the Connection Between Visceral Fat and Alzheimer’s Disease: A Comprehensive Review

Alzheimer’s disease (AD) is a growing global health issue, exacerbated by aging populations and a lack of definitive treatments.[1] Recent studies, including those by Dolatshahi et al. (2024), have highlighted a potential link between visceral fat and AD. This emerging association suggests that addressing modifiable metabolic risk factors could play a critical role in mitigating Alzheimer’s risk. Accumulation of visceral fat in midlife, particularly in the 40s and 50s, may indicate underlying brain...
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Epigenetic Imprints: The Hidden Influence on Weight Management
Metabolism Weight management Women's Health

Epigenetic Imprints: The Hidden Influence on Weight Management

Recent scientific discoveries have unveiled a fascinating aspect of weight management: the concept of "epigenetic memory" in adipose tissue. This phenomenon sheds light on why maintaining weight loss can be such a formidable challenge for many individuals[1][2]. The Epigenetic Landscape of Adipose Tissue Epigenetics refers to reversible alterations in gene activity that occur without changing the DNA sequence itself. These modifications can be influenced by various factors, including diet, physical...
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Have you been ‘Gish Galloped?’
Lifestyle Medicine Minerals Vitamins

Have you been ‘Gish Galloped?’

This is when you are in discussion with someone, or some people, whose debating method or simply their pursuit of verbal dominance is known among philosophers and rhetoricians as the ‘Gish Gallop’. The aim is simple: to defeat their opponent by burying them in a torrent of incorrect, irrelevant, or idiotic arguments. Named after one of the most vocal ‘creationists,’ Duane Gish, who notoriously used a rapid-fire approach during a debate, presenting arguments and changing topics very quickly and in...
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Is it possible that the worst disease our society faces is poor lifestyle?
Metabolism Brain Health Vitamins

Is it possible that the worst disease our society faces is poor lifestyle?

Let’s explore the most ubiquitous of lifestyle-related problems – obesity and metabolic dysfunction - and their relationship to the pervasive and increasingly common neurodegenerative disease, Alzheimer’s Disease (AD).[1] The most recent research to emphasise the link between morbidity, metabolic disruption and brain matter changes further qualified the intrinsic connection between blood sugar abnormalities and the sensitivity of certain neuronal tissues to neurodegeneration.[2] Metabolic dysfunction...
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Food As Medicine
Essential Fatty Acids Mental Health Weight management

Food As Medicine

An article in Nature Medicine out in October 2022 sets out some of the developing understanding of using food as medicine[1]. Whilst for those practitioners already immersed in this strategic use it seems obvious, it is important to remember that many practitioners are not. In turn, many people and rather depressingly most government ministers are comfortable with the benign approach to food as energy/profit only. The authors of this paper identify two important areas (in their opinion) that need...
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Specialist Probiotics & Fat-Soluble Vitamins
Probiotics Weight management Vitamins

Specialist Probiotics & Fat-Soluble Vitamins

It seems that these two long-standing areas of oral intervention in nutritional therapy and related clinical management are experiencing an ongoing and much-welcomed update in terms of application and use. Specialist Probiotics Probiotics are steadily evolving their application into specific clinical needs with recognised genera and strains (such as Akkermansia muciniphila), as opposed to their more familiar, nonspecific ecologic application. Research papers continue to show a steady progression...
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Akkermansia to the rescue
Digestive Health Detoxification Vitamins

Akkermansia to the rescue

The connection between gut microbiota and human health is well recognised and described, yet areas of uncertainty remain. This ultimate collaboration on human health has helped scientists to explain the essential mutual dependence between humans and their gut bacteria. Gut microbiota can be choreographed through passive or active strategies. The former includes hygiene, diet, lifestyle, and environment, while the latter comprises antibiotics, pre- and probiotics. In addition, dietary constituents...
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Normal, Nostalgia & the importance of Circadian Clocks
Immune Health Brain Health Sleep

Normal, Nostalgia & the importance of Circadian Clocks

“Nostalgia” was first identified in 1688 by Swiss physician Johannes Hofer who recorded the impact of nostos (homecoming) and algia (pain) on Swiss soldiers abroad. He mused that nostalgia is part of what it means to be “modern”. No longer recognised as a medical diagnosis, this gnawing feeling of loss (often exaggerated by those who seek to politicise it) speaks to a world of rapid transformation and the severing of settled identities. It can be seen as collective or personal, reflecting a societal...
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‘Here’s the thing’
Weight management Vitamins Diets

‘Here’s the thing’

In clinical practice, where lifestyle intervention is the primary strategy, it can be a real challenge to firstly motivate for change and then facilitate ongoing adoption of changed behaviours to create an evolved and enhanced health status. This can be so problematic that many primary healthcare professionals more familiar with pharmaceutical allocation find the prospect of an adaptive approach too off-putting. On the other side, there are many who pivot from pharmaceutical approaches to nutraceutical...
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Artificial Sweeteners Attack Health Via the Microbiome
Weight management Diets

Artificial Sweeteners Attack Health Via the Microbiome

Oh Boy… the journal Nature has this week (9.10.14) identified the insidious effect of consuming ‘diet’ or non caloric sweeteners on the burgeoning mass of human adipocytes and they have really taken a good run at it.[1] Non-caloric artificial sweeteners (NAS) were introduced over a century ago as means for providing sweet taste to foods without the associated high energy content of caloric sugars. NAS consumption gained much popularity owing to their reduced costs, low caloric intake and perceived...
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