Probiotics | Nutri-Link UK

The Role of Food Ingredients in the Induction of Oral Tolerance and IgA

The gastrointestinal tract serves as a critical interface between the external environment and the immune system, playing a pivotal role in the induction of oral tolerance and the production of immunoglobulin A (IgA). Oral tolerance is a phenomenon that prevents the immune system from mounting an adverse response to ingested food antigens, thereby maintaining homeostasis and preventing food allergies and autoimmune diseases. This process is essential, given the increasing prevalence of food allergies...

Probiotics Cardiovascular Health

Cardiovascular Disease and Gut Microbiota

The dark matter of the gastrointestinal microbiome, where yet to be fully discovered bacteria reside, is being steadily explored and some of the related inhabitants have been linked to the production of an enzyme that can convert artery clogging cholesterol into a more harmless form that is not absorbed by the body. In two groundbreaking studies published in Nature Microbiology and Cell, researchers have uncovered the potential of specific gut bacteria to reduce cholesterol levels, paving the way...

Immune Health Essential Fatty Acids Probiotics

Regulating T Cells

Our immune systems are heavily invested in the generation of immune tolerance (Immune tolerance is known as the state of an active, highly regulated unresponsiveness of the immune system to self-antigens or against a particular antigen that can induce an immune response in the body), and nowhere is this more concentrated than in our gastro-intestinal tract. Here the immune system faces a unique mix of an ever-changing array of food antigens and a large and complex concoction of micro-organisms. The...

Immune Health Probiotics Sleep

Sleep-Immunity-Nutrition

Over the last decades, the prevalence of sleep disorders has substantially increased globally, and it is increasingly understood to have many important health and economic-related effects.[1] A wide range of behavioural risk factors have been identified to explain, at least in part, this rise in sleep challenges. One primary driver is the evolution of the modern lifestyle which is characterised by a number of potential contributors, such as higher levels of non-resolving stress, prolonged working...

Immune Health Digestive Health Probiotics

Leveraging diet to engineer the gut microbiome to manage inflammation

The gut microbiome, i.e., the community of bacteria and other microorganisms living in the human gut, has been implicated both directly and indirectly (mediating the effects of diet) on human health. Differences in gut microbiome composition and function have been associated with a variety of chronic diseases ranging from gastrointestinal inflammatory and metabolic conditions to neurological, autoimmunity, cardiovascular, and respiratory illnesses[1]. Headline Takeaways Gut microbiome composition...

Probiotics Weight management Vitamins

Specialist Probiotics & Fat-Soluble Vitamins

It seems that these two long-standing areas of oral intervention in nutritional therapy and related clinical management are experiencing an ongoing and much-welcomed update in terms of application and use. Specialist Probiotics Probiotics are steadily evolving their application into specific clinical needs with recognised genera and strains (such as Akkermansia muciniphila), as opposed to their more familiar, nonspecific ecologic application. Research papers continue to show a steady progression...

Digestive Health Probiotics Diets

SCFAs and Skin Health

‘It’s easier to fool people than to convince them they have been fooled’ attributed to Mark Twain The relationship between the gut and skin health has been one of contention for several years. Primarily the mechanism requires there to be an agreement that the outcome of digestion impacts skin quality. This may seem an obvious connection, but for many people, this is either not understood or denied, often supported by well-meaning clinicians who are also unaware of the important connection A paper...

Digestive Health Probiotics Brain Health

Dementia and the Gut

Back in Nov 2020 the Journal of Alzheimer’s Disease published a study undertaken in Geneva, that explored the connection between the bacteria and other organisms in the human gut and their possible link to dementia[1]. A team from the University of Geneva (UNIGE) and the University Hospitals of Geneva (HUG) in Switzerland, together with Italian colleagues from the National Research and Care Centre for Alzheimer's and Psychiatric Diseases Fatebenefratelli in Brescia, University of Naples and the IRCCS...

Probiotics Vitamins Coronavirus

Pathogens and Humanity – what next?

For centuries humans have experienced a shortening of their life’s potential due to infection and trauma – in most cases the end being brutal and fast. In the Western world through various changes to public health, medicine and diplomacy, these risks have significantly reduced – and until recently, were viewed with complacency. Rather, the wealthier and developing countries have extended lifespan and morbidity time frames, by leading lifestyles that kill us less dramatically, but erode capability...

Immune Health Digestive Health Probiotics

LGG still king of Probiotics after 30 years

Lactobacillus GG (LGG) is the world’s most clinically studied probiotic. LGG was first isolated in the late ‘80s from the faecal sample of a healthy adult by the researchers Gordon and Gorbach, hence the ‘GG’ moniker. During the early studies and subsequently confirmed by multiple others, LGG is known to withstand gastric acidity and bile salts and effectively adheres to the gastrointestinal mucosa. LGG’s ability to resist gastric acidity and bile salts is a consequence of the ability of the bacterium...

The Role of Food Ingredients in the Induction of Oral Tolerance and IgA

Cardiovascular Disease and Gut Microbiota

Regulating T Cells

Sleep-Immunity-Nutrition

Leveraging diet to engineer the gut microbiome to manage inflammation

Specialist Probiotics & Fat-Soluble Vitamins

SCFAs and Skin Health

Dementia and the Gut

Pathogens and Humanity – what next?

LGG still king of Probiotics after 30 years

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