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Immune Health

The Gut-Brain Connection: Advancing Health Through Nutrition
Immune Health Digestive Health Nervous System

The Gut-Brain Connection: Advancing Health Through Nutrition

Recent scientific discoveries have unveiled a profound link between gut health and brain function, positioning dietary choices and gastrointestinal well-being at the forefront of overall health.[1] This connection is particularly significant in two areas: the use of probiotics for digestive health[2] and the application of neuronutrition in stroke recovery[3]. Probiotics and the Aryl Hydrocarbon Receptor A groundbreaking study published in Foods has shed light on how probiotics influence gut health...
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A Healthy Gut is…
Immune Health Digestive Health Phytonutrients

A Healthy Gut is…

For those involved in functional medicine, the significance of the human gut in the onset, persistence, and exacerbation of various health disorders is well established. A comprehensive care package often includes strategies for healing a dysfunctional gut, focusing on restoring the community of microorganisms and their connections both locally and systemically. While there are numerous safe and effective interventions available, the definition of a "healthy gut" can vary significantly among practitioners...
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The Role of Food Ingredients in the Induction of Oral Tolerance and IgA
Immune Health Probiotics Allergies Zinc

The Role of Food Ingredients in the Induction of Oral Tolerance and IgA

The gastrointestinal tract serves as a critical interface between the external environment and the immune system, playing a pivotal role in the induction of oral tolerance and the production of immunoglobulin A (IgA). Oral tolerance is a phenomenon that prevents the immune system from mounting an adverse response to ingested food antigens, thereby maintaining homeostasis and preventing food allergies and autoimmune diseases. This process is essential, given the increasing prevalence of food allergies...
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Immunometabolism – Nutrition is Key
Immune Health Metabolism

Immunometabolism – Nutrition is Key

Disrupted immunometabolism: The hidden culprit behind complex health issues Nutrition plays a critical role in maintaining a healthy and properly functioning immune system. The complex relationship between diet, nutrients, and immunity has significant implications for preventing and managing various diseases, from infections to chronic conditions like diabetes and cancer. Impact of micronutrients on immune function Micronutrients such as vitamins A, C, D, E, B6, B12, folate, and minerals like zinc...
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Immunity and Metabolism
Immune Health Digestive Health Food

Immunity and Metabolism

In this week (22.5.24) Diabetes UK announced that there are now almost 168,000 people aged under 40 years in the UK who live with type 2 diabetes, an increase of more than 47,000 since 2016-17. Diagnoses up 39% in 6 years, with the condition fuelled by obesity, health inequalities and junk food – meaning ultra processed food. According to the report, the total cost associated with diabetes in the UK currently stands at £23.7 billion and is predicted to rise to £39.8 billion by 2035/6. To put this...
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Focus on Leaky Gut
Immune Health Digestive Health

Focus on Leaky Gut

From ancient Ayurvedic practices to the teachings of Hippocrates, the foundational belief in medicine has always posited that the gut is central to health and disease. It is only in recent times that Western medicine has recognised gut-barrier dysfunction as a pathological phenomenon that is pivotal not just for digestive health but also for chronic allergic, inflammatory, and autoimmune diseases. Understanding the Gut Barrier's Role in Health and Disease The gut barrier, comprising the human body’s...
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Thyroid health and immunity
Immune Health

Thyroid health and immunity

Thyroid hormones (THs) are critical regulators of important physiological processes within the human body, which become particularly evident in case of TH imbalance. Both deficiency and excess of THs are associated with severe disorders affecting different organs/systems. Interestingly, hypothyroidism  is associated with increased susceptibility to infectious diseases. Yet, a comprehensive understanding of the local control of TH action within the different components of the immune system is still...
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Vitamin B12, Autoimmunity and ‘Leaky Gut’
Immune Health Digestive Health Vitamin B12

Vitamin B12, Autoimmunity and ‘Leaky Gut’

A paper released on 20th Nov 2023 in the BMJ takes a close look at B12, common practice, and determination of need[1]. This interesting review is aimed at primary care clinicians but represents a good reference paper for all healthcare professionals utilising B12 supplements and nutritional guidance to resolve B12 deficiency or dietary inadequacy. Importantly the paper explores the interindividual variations in absorption, biliary B12 excretion and the somewhat insecure determination of need and...
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A Greek Remedy for IBD and H.Pylori
Immune Health Digestive Health Phytonutrients

A Greek Remedy for IBD and H.Pylori

This headline may immediately suggest Greek islands, olive oil, and sunshine – all of which can  imbue a sense of well-being, but this review is centred on a natural product, utilised for thousands of years and a regular source of contemporary research. Chios Mastic Gum (CMG), an aromatic, white resin derived from the Pistacia lentiscus tree is a Greek health treasure. CMG was first noted by Greeks 2,500 years ago for culinary as well as medicinal applications, and praised by Pedanios Dioscorides...
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Regulating T Cells
Immune Health Essential Fatty Acids Probiotics

Regulating T Cells

Our immune systems are heavily invested in the generation of immune tolerance (Immune tolerance is known as the state of an active, highly regulated unresponsiveness of the immune system to self-antigens or against a particular antigen that can induce an immune response in the body), and nowhere is this more concentrated than in our gastro-intestinal tract. Here the immune system faces a unique mix of an ever-changing array of food antigens and a large and complex concoction of micro-organisms. The...
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