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Berberine 500 x 90 Capsules

In stock
Pure, highly concentrated berberine HCl (97%), from non-GMO Indian barberry. Berberine has a number of functions within the body. It supports healthy cholesterol and blood sugar within normal levels, and supports a normal balance of microbes in the respiratory and GI tracts and reduces inflammation as a result, and it has been shown to support a healthy intestinal permeability by improving tight junction integrity and increase the most important SCFA of butyrate, it inhibits lipid peroxidation and supports bile acid metabolism.

order before 2pm for next working day delivery (UK Only)

This information is for education purposes only. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.
Food supplements should not be used as a substitute for a balanced and varied diet.

Berberine appears to have more than one role within the body when taken as a concentrate. It has an anti-inflammatory action on the pathways of oxidative stress and inflammation that contribute to the pathogenesis of various diseases including Type 2 Diabetes Mellitus (T2DM). Specifically, Berberine has been shown to influence the various kinase and signaling pathways influencing adipocytes and immunocytes to produce interleukin-6 (IL-6) and tumour necrosis factor-α (TNF- α), thereby reducing levels of NF-kB and AMP-activated protein kinases (AMPK).

Berberine acts as an antioxidant, thereby inhibiting oxidative stress also associated with the development of insulin resistance.

Berberine promotes healthy blood sugar levels by decreasing the absorption of glucose in the gut and glucose synthesis, increases pancreatic insulin secretion, insulin sensitivity, and glucose breakdown.

Berberine supports healthy cholesterol metabolism by inhibiting cholesterol absorption in the gut, increases cholesterol excretion into the bile, decreases cholesterol synthesis.

Berberine supports a balance of gut microbiota. It increases levels of Akkermansia muciniphila, which is associated with lower BMI and healthy blood sugar management. A. muciniphila also has been shown to improve gut tight junction integrity and attenuate LPS-induced inflammation.

Berberine decreases intestinal permeability & increases gut production of butyrate, a healthy SCFA.

Berberine supports bile acid metabolism. It reduces lipid peroxidation and also has cholagogue, choleretic actions.

Directions for use

As a food supplement. 1 Capsule daily. 

Nutrition Facts

Servings size: 1 Capsule
Servings per container: 90
Per Serving:
Berberine HCI 97%
(from Indian Barberry) (root) (Berberis aristata)

† NRV not established

Ingredients: Berberine HCI, Silicon Dioxide (E551), Microcrystalline Cellulose (E460i), Rice Extract (Oryza sativa), Rice Hulls (Oryza sativa), Gum Arabic (E414), Sunflower Oil. Capsule Shell: Hydroxypropyl Methylcellulose (E464).

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