Bio-DK Caps™ supplies 125 mcg (5,000 IU) of vitamin D3, 550 mcg of vitamin K (as K1 phytonadione and K2 menaquinone-7) as a micro-emulsion for enhanced absorption and use, which is particularly important for those with malabsorption conditions.
Vitamin D deficiency is now recognised as widespread. Systemic calcium homeostasis regulation is the well-known action of vitamin D, but in addition to bone tissue, researchers have identified up to fifty different target tissues that have vitamin D receptor activity. Vitamin D is involved with the regulation of growth, reproduction, seasonal adaptation, and the immune, cardiovascular, nervous, respiratory, and neuroendocrine systems.
Vitamin K is involved with processes that help retain minerals in the bone matrix, protect soft tissue from calcification, and support nervous system functions. Vitamin D’s best known role, that of supporting bone health, is supported synergistically by vitamin K2. Vitamin D may both increase the demand for vitamin K and interact beneficially with K-dependent proteins.
Some research suggests that some problems with too much vitamin D may actually be due to insufficient vitamin K2. Many studies looking at vitamin K2 for bone and arterial functions have used menaquinone-4 (MK-4), which is a synthesised
chemical compound. MK-4 has a half-life of only 1-2 hours, so very high doses are usually needed, which require medical supervision for those on pharmaceutical blood thinners. Menaquinone-7 (MK-7) is a long chain menaquinone, naturally
derived from natto fermentation. It has a serum half-life of 3 days, and even doses as low as 45 μg/day have been found to be biologically active and effective, with little potential for negative interactions.
In addition to emulsified forms of vitamins D and K, Bio-DK Caps™ contains superoxide dismutase (SOD) and catalase. SOD is an enzyme that aids in cell repair and provides antioxidant protection against cellular damage from free radicals and environmental toxins. Catalase in an enzyme that converts hydrogen peroxide into oxygen and water, also showing strong antioxidant properties.