MM-Glycine 500mg x 240 Capsules

Glycine is the smallest of amino acid molecules, yet extremely important in liver detoxification pathways and the production of glutathione. It also supports antioxidant protection, musculoskeletal health, and restful sleep. 

Glycine works like a partner to glutamate on NMDA receptors (special brain cell switches). It attaches to one part of the receptor, which makes it tougher for glutamate to bind too strongly and overexcite the cells. This calms down the brain's activity and prevents potential damage from too much stimulation.

In GluN1/GluN3 NMDA variants, glycine exclusively activates inhibitory glycine-mediated signalling, further countering glutamatergic overexcitation. 

Preliminary evidence suggests glycine may help improve certain aspects of sleep, particularly in people with mild sleep issues. It's thought to work by lowering core body temperature (which signals the body it's time to rest), calming brain activity via NMDA receptor modulation, and supporting neurotransmitter balance like serotonin and GABA for better relaxation. (Soh et al, 2024; Thomas et al, 2024)

Metabolic Maintenance® Glycine capsules provide an alternative to the Glycine powder. This makes it possible to take when it is not easy or convenient to mix the powder into water. 

Each capsule provides 500mg of pure Glycine. 

References
Soh J, Raventhiran S, Lee JH, Lim ZX, Goh J, Kennedy BK, Maier AB. The effect of glycine administration on the characteristics of physiological systems in human adults: A systematic review. Geroscience. 2024 Feb;46(1):219-239. https://tinyurl.com/mve5nvjk 
Thomas C, Kingshott RN, Allott KM, Tang JCY, Dunn R, Fraser WD, Thorley J, Virgilio N, Prawitt J, Hogervorst E, Škarabot J, Clifford T. Collagen peptide supplementation before bedtime reduces sleep fragmentation and improves cognitive function in physically active males with sleep complaints. Eur J Nutr. 2024 Feb;63(1):323-335. https://tinyurl.com/5ups4434