GI Mend with Vegan NAG x 90 Capsules

Description

As a key organ for the absorption of nutrients and detoxification, a healthy gastrointestinal tract is the seat of systemic wellness. However, many things can compromise the integrity of the gastrointestinal lining including medications, food antigens, and gastrointestinal dysbiosis.

GI Mend provides comprehensive support for normal gastrointestinal repair, including vitamin E, zinc carnosine, vegan N-acetyl glucosamine, aloe vera extract, and the bioflavonoids rutin and quercetin.

The unique blend of nutrients and botanically-derived ingredients found in GI Mend provides the building blocks for a healthy gastrointestinal lining and delivers antioxidant protection, supporting not only the health  of the gut but also the body systemically.

N-acetyl glucosamine (NAG) provides glucosamine, utilized by the body for the synthesis of glycosaminoglycans (GAGs), an important part of healthy connective tissue. NAG may be preferred by cells of the gut lining over glucosamine in certain conditions. In some settings, abnormal breakdown of GAGs in the gut contributes to increased gut permeability and histological changes, and supplemental NAG can help replenish GAGs and support normal gut integrity. NAG supports connective tissue repair and health in the joints and skin as well as the digestive tract.

Aloe vera has a long history of traditional use to support the health of epithelial tissue. Sold in supermarkets and commonly kept as a house plant, many are familiar with its digestive- and skin-soothing properties. Aloe vera is well tolerated when taken orally, and supports the gastrointestinal mucus barrier and normal tissue repair. The polysaccharide compounds found in aloe vera also have a prebiotic effect, supporting healthy bacteria levels in the gut. Antioxidant activity provided by extracts from aloe support metabolic balance and health systemically.

Quercetin and rutin are bioflavonoids, well known for their effects of balancing the Th1:Th2 immune response. In the gut, mast cell activation and the related histamine increase contribute to increased permeability, not only in response to allergens, but also as a response to psychological stress. Quercetin and rutin both help decrease the excessive histamine response, also reducing capillary fragility. Quercetin has been shown in multiple trials to improve the integrity of intestinal tight junctions, reducing gut permeability.

The gastroprotective effects of zinc carnosine, a compound of zinc with L-carnosine, have been demonstrated clinically. Zinc carnosine helps protect the gut lining from damage due to the use of non-steroidal anti-inflammatory drugs (NSAIDs), exercise, stress, and alcohol use. Zinc is a critical nutrient for healthy intestinal barrier function, and helps to regulate the levels of occludin and claudin-3, two proteins which form the tight junctions between enterocytes.

Vitamin E completes this formula, providing additional fat-soluble antioxidant protection for the cells of the gastrointestinal lining. Vitamin E has been shown to support the health of the gut lining under the experimental stressers of radiation and hypoxia.