CALM x 60 Capsules

“Calm” is a unique botanical blend formulated to manage the body’s stress response, providing Taurine, Glycine, Rhodiola, Phosphatidylserine and Manganese. These nutrients and plant extract provide a targeted stress relief supplement for systemic balance and everyday calm.

Taurine is an important at least semi-essential amino acid for many, that benefits the brain and body. It increases GABA levels to calm neurotransmitters in the brain, promoting relaxation and happiness.

Glycine is a neurotransmitter that supports relaxation and healthy stress management. Considered one of the most inhibitory neurotransmitters in the CNS, particularly in the brainstem and spinal cord.

Rhodiola is a well-studied brain adaptogen that works to ease stress, reduce brain fog and increase focus with natural brain protection and anxiolytic properties. Helps balance brain chemicals without causing drowsiness or fatigue.

Phosphatidylserine (PS) is a naturally occurring brain-supportive phospholipid. PS supports healthy cortisol levels to improve the stress response. Studies have shown a connection with PS to enhanced mood, better immunity, and improved ability to cope with stress.

Manganese can improve the management of the excitatory neurotransmitter, histamine. Specifically, manganese is involved in the regulation of histidine decarboxylase (hdc) gene expression, which is responsible for the conversion of histidine to histamine. Manganese also plays a role in regulating histamine release and reuptake in the nervous system. Manganese is also involved in the regulation of histamine degradation. Histamine is degraded by the enzyme diamine oxidase (DAO), and manganese has been shown to up-regulate DAO expression, leading to increased histamine degradation.